The Pharmacotherapy Digital Twin as a Negotiated Model of the Patient rather than a Computational Replica

Digital-twin terminology increasingly frames the patient as a computational entity whose changing state can be reproduced, predicted, and tested under simulated interventions. In pharmacotherapy, however, no model can fully reproduce the biological, experiential, behavioral, social, and organizational conditions through which medication effects emerge. Treating a pharmacotherapy digital twin as a replica may consequently conceal model selection, incomplete data, disagreement, uncertainty, and th

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Authors

Patrick O'Connor; Grace Murphy; Niamh Walsh

Published

Jan 1, 2026

Journal or venue

Archives of Pharmacy Practice

DOI

10.51847/9r2qj1nnzc

Paper type

journal article

Source

Openalex