Application of microfluidic chip technology in pharmaceutical analysis: A...

Paper

Abstract

The development of pharmaceutical analytical methods represents one of the most significant aspects of drug development. Recent advances in microfabrication and microfluidics could provide new approaches for drug analysis, including drug screening, active testing and the study of metabolism. Microfluidic chip technologies, such as lab-on-a-chip technology, three-dimensional (3D) cell culture, organs-on-chip and droplet techniques, have all been developed rapidly. Microfluidic chips coupled with various kinds of detection techniques are suitable for the high-throughput screening, detection and mechanistic study of drugs. This review highlights the latest (2010-2018) microfluidic technology for drug analysis and discusses the potential future development in this field.

Analysis

Paper intelligence

Summary

This review highlights recent advances (2010-2018) in microfluidic chip technology for pharmaceutical analysis, including drug screening, testing, and metabolism studies, and discusses future potential.

Key findings

Microfluidic chip technologies offer new approaches for drug analysis.
These technologies are suitable for high-throughput screening, detection, and mechanistic study of drugs.
Lab-on-a-chip, 3D cell culture, organs-on-chip, and droplet techniques have developed rapidly.

Methods

Review of microfluidic technologies for drug analysis (2010-2018).

Applications

Drug screening
Active drug testing
Study of drug metabolism
High-throughput screening
Detection and mechanistic study of drugs

Confidence100%

Discovery