CAR-T and engineered T cell therapies

Clinical MedicineUpdated Oct 5, 2026Version v1

Evidence

Public papers linked to this topic and used as evidence for gaps, timelines, and knowledge views.

307 papers

Showing 277-288 of total 307 evidence records.

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2019OpenAlexDirectly related250 citations

Genetically engineered T cells for cancer immunotherapy

Dan Li; Xue Li; Weilin Zhou; Yong Huang; Xiao Liang; Lin Jiang; Xiao Yang; Jie Sun; Zonghai Li; Weidong Han; Wei Wang

Sep 19, 2019Signal Transduction and Targeted Therapy

2019CrossrefDirectly related19 citations

Accelerating chimeric antigen receptor therapy in chronic lymphocytic leukemia: The development and challenges of chimeric antigen receptor T‐cell therapy for chronic lymphocytic leukemia

Steven M. Bair; David L. Porter

May 1, 2019American Journal of Hematology

2019OpenAlexDirectly related1,787 citations

Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma

Noopur Raje; Jesús G. Berdeja; Yi Lin; David S. Siegel; Sundar Jagannath; Deepu Madduri; Michaela Liedtke; Jacalyn Rosenblatt; Marcela V. Maus; Ashley Turka; Lyh-Ping Lam; Richard A. Morgan; Kevin M. Friedman; Monica Massaro; Julie Wang; Greg Russotti; Zhihong Yang; Timothy Campbell; Kristen Hege; Fabio Petrocca; M. Travis Quigley; Nikhil C. Munshi; James N. Kochenderfer

May 1, 2019New England Journal of Medicine

2018OpenAlexDirectly related2,398 citations

Chimeric Antigen Receptor Therapy

Carl H. June; Michel Sadelain

Jul 4, 2018New England Journal of Medicine

2018OpenAlexSupporting evidence3,271 citations

CAR T cell immunotherapy for human cancer

Carl H. June; Roddy S. O’Connor; Omkar U. Kawalekar; Saba Ghassemi; Michael C. Milone

Mar 22, 2018Science

2018OpenAlexDirectly related168 citations

Functional TCR T cell screening using single-cell droplet microfluidics

Aude I. Ségaliny; Guideng Li; Lingshun Kong; Ci Ren; Xiaoming Chen; Jessica K. Wang; David Baltimore; Guikai Wu; Weian Zhao

Jan 1, 2018Lab on a Chip

2018CrossrefSupporting evidence0 citations

Adoptive CD8+ T-cell Therapy Possibilities

Sofia Iakushina

Jan 1, 2018Pharmaceutical Drug Regulatory Affairs Journal

2017OpenAlexDirectly related6,114 citations

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma

Sattva S. Neelapu; Frederick L. Locke; Nancy L. Bartlett; Lazaros J. Lekakis; David B. Miklos; Caron A. Jacobson; Ira Braunschweig; Olalekan O. Oluwole; Tanya Siddiqi; Yi Lin; John M. Timmerman; Patrick J. Stiff; Jonathan W. Friedberg; Ian W. Flinn; André Goy; Brian T. Hill; Mitchell R. Smith; Abhinav Deol; Umar Farooq; Peter A. McSweeney; Javier Muñoz; Irit Avivi; Januario E. Castro; Jason R. Westin; Julio C. Chávez; Armin Ghobadi; Krishna V. Komanduri; Ronald Levy; Eric D. Jacobsen; Thomas E. Witzig; Patrick M. Reagan; Adrian Bot; John M. Rossi; Lynn Navale; Yizhou Jiang; Jeff Aycock; Meg Elias; David Chang; Jeff Wiezorek; William Y. Go

Dec 10, 2017New England Journal of Medicine

2017OpenAlexSupporting evidence512 citations

Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma

Martin Lauss; Marco Donia; Katja Harbst; Rikke Andersen; Shamik Mitra; Frida Rosengren; Maryem Salim; Johan Vallon‐Christersson; Therese Törngren; Anders Kvist; Markus Ringnér; Inge Marie Svane; Göran Jönsson

Nov 17, 2017Nature Communications

2017OpenAlexDirectly related458 citations

Phase I Escalating-Dose Trial of CAR-T Therapy Targeting CEA+ Metastatic Colorectal Cancers

Chengcheng Zhang; Zhe Wang; Zhi Yang; Meiling Wang; Shiqi Li; Yunyan Li; Rui Zhang; Zhouxing Xiong; Zhihao Wei; Junjie Shen; Yongli Luo; Qianzhen Zhang; Limei Liu; Hong Qin; Wei Liu; Feng Wu; Wei Chen; Feng Pan; Xianquan Zhang; Ping Bie; Houjie Liang; Gabriele Pecher; Cheng Qian

Mar 31, 2017Molecular Therapy

2017OpenAlexDirectly related769 citations

Global Manufacturing of CAR T Cell Therapy

Bruce L. Levine; James Miskin; Keith Wonnacott; Christopher Hunt Keir

Jan 1, 2017Molecular Therapy — Methods & Clinical Development

2016OpenAlexDirectly related1,889 citations

Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

Christine E. Brown; Darya Alizadeh; Renate Starr; Lihong Weng; Jamie R. Wagner; Araceli Naranjo; Julie R. Ostberg; M. Suzette Blanchard; Julie Kilpatrick; Jennifer Simpson; Anita Kurien; Saul J. Priceman; Xiuli Wang; Todd L. Harshbarger; Massimo D’Apuzzo; Julie A. Ressler; Michael C. Jensen; Michael E. Barish; Mike Y. Chen; Jana Portnow; Stephen J. Forman; Behnam Badie

Dec 28, 2016New England Journal of Medicine